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Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Adapalene/Benzoyl Peroxide Topical Gel (ADAPALENE/BENZOYL PEROXIDE GEL - TOPICAL)

For acne.

Brand Name(s): Epiduo

Generic Name: Adapalene/Benzoyl Peroxide

Instructions

DO NOT take this medicine by mouth.

Apply a thin layer to the affected area and rub it in.

Wash the area first. Apply the medicine to the skin and then allow to dry for a few minutes.

Keep this medicine at room temperature.

This medicine should only be used on the skin.

Do not use any other acne medicines on your skin while using this medicine unless instructed by your doctor.

Avoid getting the medicine in the eyes, nose, or mouth. Wash the medicine off your fingers after applying it.

Avoid prolonged or excessive sunlight exposure. Use sunscreen lotion with SPF 15 or higher.

Use the medicine only on normal looking skin. Avoid areas of the skin that are red, have scrapes, or damaged.

Wash your hands before and after handling this medicine.

Do not touch your eyes, nose or mouth after handling the medicine.

If medicine gets in your eyes, rinse well with cool water.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Do not take the medicine more than once during 24 hours.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.

Women who are pregnant or in their childbearing years should not touch or handle this medicine. This medicine can be absorbed through the woman's skin and harm the unborn baby.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Do not share this medicine with anyone who has not been prescribed this medicine.

Seek medical attention if you see any signs of a serious infection. These signs include pain, increasing redness or pus where this medicine is being used.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • burning or stinging
  • dry skin
  • flaking or peeling skin
  • skin irritation where medicine is applied
  • increased risk of sunburn

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • blistering or peeling of the skin

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.